Dıc Nedir Tıp
kaynağı değiştir]
DIC, çok sayıda klinik bozukluğun bir belirtisi olarak ortaya çıkabildiği gibi yaygın endotel hasarı en önemli sebeptir. Bundan başka genel olarak DIC sebepleri;
- Septisemi[4]
- Travma (Şiddetli doku hasarı, Kafa darbeleri, Yağ embolisi)
- Kanser (Miyeloproliferatif hastalıklar, Solid tümörler (Pankreatik karsinom, Prostatik karsinom gibi))
- Obstetrik komplikasyonlar (Amnion sıvısı embolisi, Plasental ayrılma)
- Dolaşım bozuklukları (Dev hemangioma (Kasabach-Merritt sendromu), Aort anevrizması)
- Toksin reaksiyonları (yılan zehiri, ilaçlar, amfetamin gibi)
- Immunolojik bozukluklar (Yaygın alerjik reaksiyon, Kan nakil reaksiyonları, Doku reddi)
- Endotoksik şok
Şiddetli Travma[değiştir kaynağı değiştir]
- ^Marder VJ, Feinstein DI, Francis CW, Colman RW. Consumptive thrombohemorrhagic disorders. In: Colman RW, Hirsh J, Marder VJ, Salzman EW, eds. Hemostasis and thrombosis: basic principles and clinical practice. 3rd ed. Philadelphia: J.B. Lippincott,
- ^Mller-Berghaus G, ten Cate H, Levi MM. Disseminated intravascular coagulation. In: Verstraete M, Fuster V, Topol EJ, eds. Cardiovascular thrombosis: thrombocardiology and thromboneurology. 2nd ed. Philadelphia: Lippincott-Raven,
- ^abGando S, Kameue T, Nanzaki S, Nakanishi Y. Disseminated intravascular coagulation is a frequent complication of systemic inflammatory response syndrome. Thromb Haemost ;
- ^Thijs LG, de Boer JP, de Groot MCM, Hack CE. Coagulation disorders in septic shock. Intensive Care Med ;Suppl 1:S8-S
- ^Roumen RMH, Hendriks T, van der Ven-Jongekrijg J, et al. Cytokine patterns in patients after major vascular surgery, hemorrhagic shock, and severe blunt trauma: relation with subsequent adult respiratory distress syndrome and multiple organ failure. Ann Surg ;
- ^Colman RW, Rubin RN. Disseminated intravascular coagulation due to malignancy. Semin Oncol ;
- ^Sarris AH, Kempin S, Berman E, et al. High incidence of disseminated intravascular coagulation during remission induction of adult patients with acute lymphoblastic leukemia. Blood ;
- ^Weiner CP. The obstetric patient and disseminated intravascular coagulation. Clin Perinatol ;
- ^Sibai BM, Spinnato JA, Watson DL, Hill GA, Anderson GD. Pregnancy outcome in cases with severe preeclampsia. Obstet Gynecol ;
- ^Szlachetka DM. Kasabach-Merritt syndrome: a case review. Neonatal Netw ;17(1) [Erratum, Neonatal Netw ;17(3)]
- ^Aboulafia DM, Aboulafia ED. Aortic aneurysm-induced disseminated intravascular coagulation. Ann Vasc Surg ;
- ^Ruggenenti P, Lutz J, Remuzzi G. Pathogenesis and treatment of thrombotic microangiopathy. Kidney Int Suppl ;SS
- ^Furlan M, Robles R, Galbusera M, et al. Von Willebrand factorÐcleaving protease in thrombotic thrombocytopenic purpura and the hemolyticÐuremic syndrome. N Engl J Med ;